The most important MDCAT topics by subject, and where the marks actually sit. Biology carries 45% of the paper, so start there.

Biology is 45% of MDCAT (81 of 180 MCQs) and Chemistry is 25% (45 MCQs), so the most important MDCAT topics live in those two subjects. Start with Biology, then Chemistry, but still cover the full syllabus.
The most important MDCAT topics are where your marks live. This guide to MDCAT important topics shows where to focus first. When time is short, you cannot study every chapter with equal weight. The most important MDCAT topics are the ones that carry the most marks, and that is decided by how the 180 questions are split across subjects. Biology alone is 45% of the paper. This guide shows where the marks sit subject by subject so you focus on the right chapters first, then fill in the rest.
One honest note up front. PMDC sets the subject weightage and the syllabus, but it does not publish how many MCQs come from each individual chapter. So the chapter-level priorities below are based on exam trends and past papers, not an official chapter count. Treat them as a smart starting order, not a guarantee.
The most important MDCAT topics are in Biology and Chemistry, because together they make up 70% of the paper. MDCAT has 180 MCQs total: Biology 81 (45%), Chemistry 45 (25%), Physics 36 (20%), English 9 (5%), and Logical Reasoning 9 (5%). Get Biology and Chemistry strong and you have already covered 126 of the 180 marks.
| Subject | MCQs | Weightage | Priority |
|---|---|---|---|
| Biology | 81 | 45% | Highest |
| Chemistry | 45 | 25% | High |
| Physics | 36 | 20% | Medium |
| English | 9 | 5% | Quick wins |
| Logical Reasoning | 9 | 5% | Quick wins |
The difficulty split is also fixed by PMDC: roughly 15% easy, 70% moderate, and 15% hard. Most of the paper is moderate, so the goal is steady accuracy across many chapters, not chasing a handful of hard questions.
Study Biology first. At 81 MCQs it is almost half the paper, and a strong Biology score can carry your aggregate even if another subject slips. After Biology, move to Chemistry, then Physics, and keep English and Logical Reasoning as short daily practice.
Here is a simple order that matches where the marks are:
In Biology, focus first on the chapters that repeat heavily in past papers: cell biology, biological molecules and enzymes, human physiology, and genetics. These tend to be question-dense across years. Because Biology is 45% of the paper, every chapter you skip here costs more than a skipped chapter anywhere else.
For a full chapter walkthrough and practice questions, read our MDCAT Biology guide.
In Chemistry, the heaviest-return areas are atomic structure, the periodic table and periodicity (s and p block trends), chemical bonding, and the reaction-based organic chapters. Periodic trends like ionization energy and atomic radius show up often, so they are worth locking in early.
Our MDCAT Chemistry guide breaks these chapters down with worked MCQs.
Physics is 20% of the paper and rewards concept clarity over memorising. Prioritise the mechanics and electricity chapters, where most numericals come from, and make sure your formulas are second nature. Force and motion, work and energy, electrostatics, and current electricity tend to carry weight.
See our MDCAT Physics guide for the formula list and practice sets.
No. Prioritising is about order, not skipping. English and Logical Reasoning are only 5% each, but those 18 marks are usually easy and fast, and losing them for no reason can drop you below a tight merit cutoff. Study the high-yield chapters first, then come back and cover the full syllabus before the exam.
Prioritise by weight, but finish the full syllabus. A skipped chapter is a question someone else gets right.
The fastest way to find your real weak chapters is to practise topic by topic and watch your accuracy. You can practice MDCAT MCQs by subject on Parhlai, track which chapters you miss most, and spend your remaining days where they actually move your score.
Cover image: "image" by Unknown via Unsplash, licensed under UNSPLASH LICENSE.
Co-Founder, Parhlai
Hadi Khan is a co-founder of Parhlai. He writes practical, fact-checked guides on entry-test preparation, university admissions, and study strategy for Pakistani students.

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